Drug Standards
Medchemexpress LLC (S)-ketorolac | 66635-92-5 | 99.3% | 255.27 g/mol | C15H13NO3 | 10 MG
(S)-Ketorolac is the S-enantiomer of ketorolac, a nonsteroidal anti-inflammatory agent that potently inhibits cyclooxygenase enzymes COX-1 and COX-2. Supplied as a small-molecule research reagent, it is used in studies of prostaglandin synthesis, inflammation signaling, and COX enzyme activity.
- High purity suitable for research uses.
- Potent inhibitor of COX-1 and COX-2 for inflammation studies.
- Provided as a solid small-molecule reagent with formula C15H13NO3.
- Molecular weight 255.27 g/mol.
- Documentation available: SDS, COA, and analytical data.
- Available in small pack sizes including 10 mg.
TARGETMOL CHEMICALS INC TENOFOVIR AMIBUFENAMIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Tenofovir amibufenamide (HS-10234) (HS-10234) is a Tenofovir prodrug an antiviral compound with oral activity. Tenofovir amibufenamide inhibits hepatitis B virus (HBV) and can be used in chronic hepatitis B (CHB) studies. purity: 99%
Medchemexpress LLC Methylprednisolone-d2 | 83-43-2 | 99.1% | 1 MG
Methylprednisolone-d2 is the deuterium labeled Methylprednisolone, a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. It improves severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Folic acid (Standard) | 59-30-3 | 98.4% | 441.40 | 50 MG
Folic acid (Standard) is the analytical standard of Folic acid, intended for research and analytical applications. Folic acid (Vitamin B9) is an orally active essential nutrient from the B complex group of vitamins. It exhibits an antidepressant-like effect. Folic acid sodium can reduce the risk of neonatal neural tube defects. Folic acid is used in the research of megaloblastic and macrocytic anemias due to folic deficiency. This compound is an analytical standard and reference standard supplied for assays.
- Analytical standard for folic acid
- Intended for research and analytical applications
- Orally active essential nutrient from the B complex group of vitamins
- Exhibits an antidepressant-like effect
- Used to reduce the risk of neonatal neural tube defects
- Used in research of megaloblastic and macrocytic anemias due to folic deficiency
- Suitable for HPLC, GC, and MS experiments
Medchemexpress LLC Naloxone benzoylhydrazone | 119630-94-3 | MFCD05662358 | 98.4% | 445.51 | C26H27N3O4 | 1 MG
Naloxone benzoylhydrazone is a naloxone-derived small molecule described as a mixed agonist/antagonist with prototypic κ3-opioid receptor agonist activity; it is used in pharmacology research to investigate opioid receptor signaling and analgesic responses.
- Prototypic κ3-opioid receptor agonist activity.
- Partial agonist at μ and δ opioid receptors.
- Antagonist activity at opioid-like NOP receptors.
- High reported purity (98.36%).
- Solid form with defined storage conditions for stability.
Medchemexpress LLC Ticagrelor impurity 26 | 1644461-85-7 | 99.4% | 538.57 g/mol | C23H28F2N6O5S | 10 MG
Ticagrelor impurity 26 is a characterized impurity of the antiplatelet agent ticagrelor provided as a high-purity analytical reference material for impurity profiling and method development.
- Reported purity 99.39%.
- CAS number 1644461-85-7.
- Molecular formula C23H28F2N6O5S; molecular weight 538.57 g/mol.
- Intended for HPLC and LC-MS method development and impurity identification.
- Supplied in small quantities suitable for analytical use.
Medchemexpress LLC Nintedanib impurity 5 | 676326-36-6 | C12H11NO4 | 25 MG
Nintedanib impurity 5 is an impurity of Nintedanib. This product is intended for research use only and has not been fully validated for medical applications.
- Store at room temperature for 3 years.
- When in solvent, store at -80°C for 2 years.
- When in solvent, store at -20°C for 1 year.
Medchemexpress LLC Atazanavir (sulfate) | 229975-97-7 | 99.7% | 802.93 | 5 MG
Atazanavir sulfate is a highly selective and orally active HIV-1 protease inhibitor with blood-brain barrier permeability. It acts as a substrate and inhibitor of CYP3A4, and an inhibitor of P-glycoprotein (P-gp). It also functions as a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM, and inhibits cardiac fibrosis, hyperlipidemia, and induces malignant glioma death.
- Highly selective and orally active HIV-1 protease inhibitor
- Blood-brain barrier permeability
- Substrate and inhibitor of CYP3A4
- Inhibitor of P-glycoprotein (P-gp)
- SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM
- Inhibits cardiac fibrosis and hyperlipidemia
- Induces malignant glioma death
Medchemexpress LLC Febantel | 58306-30-2 | 99.9% | 446.48 | 1 G
Febantel is an oral dewormer used to treat gastrointestinal nematodes in sheep, as well as roundworm and tapeworm infections in poultry and livestock. It also inhibits the embryonic development of mouse hairworms and whipworm eggs.
- Acts as an oral dewormer
- Inhibits embryonic development of certain parasites
- Suitable for research use only
Medchemexpress LLC Febantel | 58306-30-2 | 99.9% | 446.48 | 10 G
Febantel is an oral dewormer utilized for treating gastrointestinal nematodes in sheep, as well as roundworm and tapeworm infections in poultry and livestock. It also hinders the embryonic development of mouse hairworms and whipworm eggs.
- Treats gastrointestinal nematodes in sheep
- Treats roundworm and tapeworm infections in poultry and livestock
- Inhibits embryonic development of mouse hairworms
- Inhibits embryonic development of whipworm eggs
Medchemexpress LLC Ticagrelor impurity 5 | 1863036-49-0 | C26H32F2N6O5S | 5 MG
Ticagrelor impurity 5 is an impurity of Ticagrelor (HY-10064). This product requires specific storage conditions to maintain stability and efficacy.
- Store at 4°C under nitrogen
- When in solvent, store at -80°C for up to 6 months
- When in solvent, store at -20°C for up to 1 month under nitrogen
Enzo Life Sciences ABT-888 (1mg). CAS: 912445-05-7
Potent inhibitor of PARP-1 and PARP-2 (potency ≤5nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radiopotentiation. Is toxic to both oxic and hypoxic cells. Enantiomeric purity ≥97% suitable for in vivo studies. Does not show inherent cytotoxicity and shows no single agent activity in tumor models. Has excellent bioavailability and good blood-brain permeation. Increases tumor growth delay resulting from radiation and DNA-damaging agents. Alternative name: 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide . dihydrochloride. Purity: ≥98% (HPLC). Appearance: Colorless to white crystalline solid. Solubility: Soluble in water or DMSO. Long Term Storage: -20°C.
Medchemexpress LLC Porcn-IN-1 | 2036044-77-4 | 99.6% | 410.44 | 50 MG
Porcn-IN-1 is a potent porcupine inhibitor with an IC50 of 0.5±0.2 nM. It potently inhibits the secretion of Wnt3A. Porcupine is an enzyme that catalyzes the addition of palmitoleate to a serine residue in Wnt proteins, a process required for their secretion.
- Potent porcupine inhibitor
- Inhibits secretion of Wnt3A
- Targets Porcupine and is involved in the Stem Cell/Wnt pathway
- As potent as clinical compound LGK974 in cell-based STF reporter gene assay
- Demonstrates moderate clearance in human and rat liver microsomes
- Exhibits high clearance with mouse microsomes
Medchemexpress LLC Hexanoylglycine-d11 | 24003-67-6 | 99.7% | 184.28 | 10 MG
Hexanoylglycine-d11 is the deuterium labeled Hexanoylglycine. It can be used as a tracer and as an internal standard for quantitative analysis. Deuteration, the substitution of deuterium for hydrogen, has gained attention for its potential impact on the pharmacokinetic and metabolic profiles of drugs. Stable heavy isotopes like hydrogen, carbon, and other elements are incorporated into drug molecules as tracers for quantitation during drug development.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Spironolactone (Standard) | 52-01-7 | 98.55% | 25 MG
Spironolactone is an orally active analytical standard intended for research and analytical applications. It functions as an aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM, and also acts as a potent androgen receptor antagonist with an IC50 of 77 nM. Additionally, it has been shown to promote autophagy in podocytes.
- Orally active.
- Aldosterone mineralocorticoid receptor antagonist.
- Androgen receptor antagonist.
- Promotes autophagy in podocytes.
- Used in qualitative, quantitative and methodological research experiments.